3,4-二氯-α，α，α-三氟甲苯 — 登记平台物质详情

① 化学品基本信息

化学品名称

3,4-二氯-α，α，α-三氟甲苯

英文名称

3,4-dichloro-α,α,α-trifluorotoluene

CAS号

328-84-7

② 标签要素

危险性类别

皮肤腐蚀/刺激,类别2,特异性靶器官毒性-一次接触,类别3（呼吸道刺激）

GHS警示词

警告

GHS分类来源

自分类

象形图

GHS07

危险性说明

H315:造成皮肤刺激H335:可能引起呼吸道刺激

③ 理化特性

外观与性状

透明无色液体。

熔点（℃）

-13～-12 deg

沸点/沸程（℃）

173～174

相对密度（水=1）

无资料

相对蒸气密度（空气=1）

无资料

饱和蒸气压（kPa）

0.31，25℃

辛醇/水分配系数（LogKow）

4.24 (20 °C)

闪点（℃）

65 (150 F)

自燃温度（℃）

无资料

爆炸下限（%）

无资料

爆炸上限（%）

无资料

溶解性

Soluble in petroleum ether and acetonitrile.[Yurawecz MP

J Assoc Off Anal Chem 62(1)

36-40 (1979)] **PEER REVIEWED** In water: negligible - 15 mg/l @ 25 deg C (est)[ITC/USEPA

密度

1.478

④ 危害信息

活性反应

与强氧化剂接触，有发生火灾和爆炸的危险。

禁配物

氧化剂、卤素。

中毒表现

造成皮肤刺激，可能引起呼吸道刺激。

⑤ 应急处置措施

急救措施

A) DECONTAMINATION - 1) INHALATION: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with an inhaled beta2-adrenergic agonist. Consider systemic corticosteroids in patients with significant bronchospasm. B) IRRITATION - 1) Respiratory tract irritation, if severe, can progress to pulmonary edema which may be delayed in onset up to 24 to 72 hours after exposure in some cases. C) ACUTE LUNG INJURY - 1) ACUTE LUNG INJURY: Maintain ventilation and oxygenation and evaluate with frequent arterial blood gases and/or pulse oximetry monitoring. Early use of PEEP and mechanical ventilation may be needed. D) BRONCHOSPASM - 1) If bronchospasm and wheezing occur, consider treatment with inhaled sympathomimetic agents. E) OBSERVATION CRITERIA - 1) Carefully observe patients with inhalation exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary. 2) Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved.A) GASTRIC LAVAGE 1) Significant esophageal or gastrointestinal tract irritation or burns may occur following ingestion. The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. 2) GASTRIC LAVAGE: Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in the head down left lateral decubitus position or by endotracheal intubation. Control any seizures first. a) CONTRAINDICATIONS: Loss of airway protective reflexes or decreased level of consciousness in unintubated patients; following ingestion of corrosives; hydrocarbons (high aspiration potential); patients at risk of hemorrhage or gastrointestinal perforation; and trivial or non-toxic ingestion. B) ACTIVATED CHARCOAL 1) Activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. In general, metals and acids are poorly bound and patients ingesting these materials will not likely benefit from activated charcoal administration. a) Activated charcoal should not be given to patients ingesting strong acidic or basic caustic chemicals. Activated charcoal is also of unproven value in patients ingesting irritant chemicals, where it may obscure endoscopic findings when the procedure is justified. 2) ACTIVATED CHARCOAL: Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. C) DILUTION - 1) Immediate dilution with milk or water may be of benefit in caustic or irritant chemical ingestions. 2) DILUTION: If no respiratory compromise is present, administer milk or water as soon as possible after ingestion. Dilution may only be helpful if performed in the first seconds to minutes after ingestion. The ideal amount is unknown; no more than 8 ounces (240 mL) in adults and 4 ounces (120 mL) in children is recommended to minimize the risk of vomiting. D) IRRITATION - 1) Observe patients with ingestion carefully for the possible development of esophageal or gastrointestinal tract irritation or burns. If signs or symptoms of esophageal irritation or burns are present, consider endoscopy to determine the extent of injury. E) OBSERVATION CRITERIA - 1) Carefully observe patients with ingestion exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary. 2) Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved.A) OVERVIEW 1) DERMAL DECONTAMINATION - a) DECONTAMINATION: Remove contaminated clothing and jewelry and place them in plastic bags. Wash exposed areas with soap and water for 10 to 15 minutes with gentle sponging to avoid skin breakdown. A physician may need to examine the area if irritation or pain persists (Burgess et al, 1999). 2) PESTICIDES - a) DECONTAMINATION: Remove contaminated clothing and jewelry and place them in plastic bags. Wash exposed areas with soap and water for 10 to 15 minutes with gentle sponging to avoid skin breakdown. A physician may need to examine the area if irritation or pain persists (Burgess et al, 1999). 3) IRRITATION - a) Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines. 4) DERMAL ABSORPTION - a) Some chemicals can produce systemic poisoning by absorption through intact skin. Carefully observe patients with dermal exposure for the development of any systemic signs or symptoms and administer symptomatic treatment as necessary.A) DECONTAMINATION: Remove contact lenses and irrigate exposed eyes with copious amounts of room temperature 0.9% saline or water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist after 15 minutes of irrigation, the patient should be seen in a healthcare facility.

泄漏应急处理

小量泄漏:用砂土或其他不燃材料吸收。使用洁净的无火花工具收集吸收材料。大量泄漏:构筑围堤或挖坑收容。用泡沫覆盖,减少蒸发。用防爆泵转移至槽车或专用收集器内。

灭火方法

消防人员必须佩戴正压式消防空气呼吸器，可能接触化学品的应穿消防员一级化学防护服。根据化学品性质选择适用的灭火剂，在上风向灭火。疏散位于下风向的人员。在火灾区域设置围堰。喷水冷却容器，可能的话将容器从火场移至空旷处。在灭火同时必须注意计算可能发生沸溢、喷溅的时间和观察是否有沸溢、喷溅的征兆。处在火场中的容器若已变色或从安全泄压装置中产生异常声音，必须马上撤离。尽量使用低压灭火剂流或雾状水，避免化学品溅出。盛装容器材质不能与泄漏化学品发生反应。宜调制相应的中和剂进行稀释中和。

⑥ 安全技术说明书

该物质在登记平台未登记 SDS 文件。

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